Die medikamentenbedingte Osteonekrose des Kiefers (MRONJ) ist eine schwere Nebenwirkung, die durch die Anwendung von antiresorptiven, antiangiogenen Medikamenten verursacht wird.
Die Behandlung von MRONJ ist schwierig und oft langwierig. Die kontrollierten Studien mit leukozyten- und plättchenreichem Fibrin (LPRF) zeigen hier einen 60-100% Heilungserfolg und können gut mit einer fluoreszenzgeführte Chirurgie (85-90% Erfolg) kombiniert werden. Die Studien auf diesem Gebiet werden mit großer Spannung fortgesetzt.
Für weiterführende Informationen: Govaerts et al. Adjuvant therapies for MRONJ: A systematic review. Bone. 2020 Dec; 141:115676. doi: 10.1016/j.bone.2020.115676.
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